Floyd Mayweather Jr. vs. Shane Mosley, billed as Who R U Picking?, was a boxing welterweight non-title superfight. The bout was held on May 1, 2010, before a "sellout" crowd of 15,117 at the MGM Grand Garden Arena in Las Vegas, Nevada, United States. The match was put together after Andre Berto pulled out of his scheduled January 30 unification bout against Mosley.

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