Final Fantasy Type-0 is set within Orience, a land divided between four nations or "Crystal States". Each nation has crystals of power based on the Four Symbols, which are in turn their national emblems. The Dominion of Rubrum uses the Vermillion Bird Crystal, which controls magic; the Milites Empire controls the White Tiger Crystal, containing the power of science and weapons; the Kingdom of Concordia uses the Azure Dragon Crystal, containing the power of Dragons; and the Lorican Alliance is home to the Black Tortoise Crystal, containing the power of shielding. Each nation has an academy, or Peristylium, to research and protect the country's respective crystal. The crystals have the ability to mark humans as their countries' servants. These servants, called l'Cie, are branded with a symbol and are given a "Focus", a task to complete. While blessed with long life and the ability to transform into crystal, l'Cie are cursed to lose their memories over time. The people of Orience also lose their memories of the dead, so they will not be held back by any past regrets and continue strengthening their souls through conflict, a mechanism put in place by the crystals for the convenience of the deities who crafted them. The main aim of many characters is to become Agito, a legendary figure who will appear and save the world from Tempus Finis, an apocalyptic event that will destroy Orience.

Final Fantasy Type-0 is set within Orience, a land divided between four nations or "Crystal States". Each nation has crystals of power based on the Four Symbols, which are in turn their national emblems. The Dominion of Rubrum uses the Vermillion Bird Crystal, which controls magic; the Milites Empire controls the White Tiger Crystal, containing the power of science and weapons; the Kingdom of Concordia uses the Azure Dragon Crystal, containing the power of Dragons; and the Lorican Alliance is home to the Black Tortoise Crystal, containing the power of shielding. Each nation has an academy, or Peristylium, to research and protect the country's respective crystal. The crystals have the ability to mark humans as their countries' servants. These servants, called l'Cie, are branded with a symbol and are given a "Focus", a task to complete. While blessed with long life and the ability to transform into crystal, l'Cie are cursed to lose their memories over time. The people of Orience also lose their memories of the dead, so they will not be held back by any past regrets and continue strengthening their souls through conflict, a mechanism put in place by the crystals for the convenience of the deities who crafted them. The main aim of many characters is to become Agito, a legendary figure who will appear and save the world from Tempus Finis, an apocalyptic event that will destroy Orience.